Discussion
Enhancing gut-brain communication reversed cognitive decline, improved memory formation in aging mice
steve1977: ... in mice.
fnord77: [delayed]
theusus: Mice mice mice. Tell me when you test on humans
j45: in mice is clearly in the subhead.The connection between gut-brain has been studied in humans, as well as teh effect of diet and gut bacteria on brain functions.
vidarh: And in this case it sounds like the pathway to determining if this has an effect in humans as well might be relatively short given there is a pool of patients receiving vagus nerve stimulation for other things that might provide data.
maxall4: I smell bad data. This sounds too good to be true and most studies of this kind have turned out to be false a few years down the line.
inanutshellus: Everyone's "pooing" on the article because it's just talking about affecting mice, but stories of gut biota affecting humans behavior have been documented for a while. Memory gain is noteworthy, which is their point, but everyone's just knee-jerk smirking so ... here's a few random articles to gross you out about the ... gross ... world of trading microbiota and, for better or worse, changing your personality.[1][2] [1] https://www.psychologytoday.com/us/blog/the-behavioral-microbiome/202404/hacking-an-individuals-personality-through-their-gut-contents [2] https://www.abc.net.au/news/2025-07-28/faecal-microbiota-transplant-credited-with-curing-bipolar/105541522
1shooner: This seems to be a recent anti-science meme to dismiss studies that use mouse models. I'm sure there is an interesting line of discussion about the strengths and limits of those models, but that's probably a complex, nuanced thread to pull, not something you blow off with a hand-waving internet comment.
inanutshellus: To some degree the other posts are just pointing out the misleading "assumed protagonist" of the title (which doesn't mention mice) but I was surprised to see that the majority of posts boiled down to "eek! mice!"
