Discussion
Subfictional Studios
functionmouse: Dead URL
d-us-vb: Worked for me.
ser13: Archive link: https://web.archive.org/web/20260120080248/https://subfictio...
ChrisMarshallNY: Hugged to death.MS sucks. There’s varying degrees, though. I know folks that have it now, and ones that died from it.Some of the treatments aren’t very nice. I knew one chap that was on Interferon, for life.
throwawaymsjs: The modern treatments are much more effective than anybody had expected, Ocrecus went from something used in the last resort to standard care in less than a decade. I have no issue with it whatsoever though that’s not the case for everyone, and it’s now available as a 6 month injection rather than a 8+ hour infusion thankfully. The older drugs were unbelievably bad (blindness, infection, you name it), but Ocrecus has been very tame in comparison. Can’t get vaccinated for Measles (and have 0 immunity) but that’s my only limitation really.
prplfsh: https://www.astrazeneca.com/what-science-can-do/topics/next-...AstraZeneca is doing some really interesting research in this area - cell therapies that reset the immune system to eliminate the dysfunctional cells driving autoimmune disease, and then allow a healthy immune system to rebuild (for diseases like lupus, rheumatoid arthritis, and multiple sclerosis).
konschubert: Today, there is also AHSCT.There are already clinics where they basically remove your immune system and give you a new one. If you don’t die in the process, you are likely to be cured of MS.(Any existing damage will remain.)Currently this is reserved for the most quickly progressing cases but if we can make this safer and cheaper, it might in future be applied as an early stage cure, so people can go on to live healthy lives.That being said, Astra Zenecas approach does seem much safer, if it’s proven to be effective!
SmellTheGlove: Yeah AHSCT is no joke. I mentioned in another comment my wife has MS - diagnosed last year in her mid 40s with thankfully no severe impairment. They discussed AHSCT with us but didn’t recommend it unless another disease modifying treatment didn’t work. Thankfully, Tysabri seems to be working well for her.My mom passed from leukemia years ago. Or rather, from an infection as she was starting HSCT. I’m sure it’s safer than it was 30 years ago, but being without an immune system for a period of time really is still a last resort.
